If the private key is lost, the bitcoin network will not recognize any other evidence of ownership; the coins are then unusable, and effectively lost. For example, in 2013 one user claimed to have lost 7,500 bitcoins, worth $7.5 million at the time, when he accidentally discarded a hard drive containing his private key. A backup of his key(s) would have prevented this.
If you've made it this far, then congratulations! There is still so much more to explain about the system, but at least now you have an idea of the broad outline of the genius of the programming and the concept. For the first time we have a system that allows for convenient digital transfers in a decentralized, trust-free and tamper-proof way. The repercussions could be huge.
For one, proof of work prevents miners from creating bitcoins out of thin air: they must burn real energy to earn them. And two, proof of work ossifies Bitcoin’s history. If an attacker were to try and change a transaction that happened in the past, that attacker would have to redo all of the work that has been done since to catch up and establish the longest chain. This is practically impossible and is why miners are said to “secure” the Bitcoin network.
In order to have an edge in the mining competition, the hardware used for Bitcoin mining has undergone various developments, starting with the use the CPU. The CPU can perform many different types of calculations including Bitcoin mining. In the beginning, mining with a CPU was the only way to mine Bitcoins and was done using the original Satoshi client. Unfortunately, with the nature of most CPU in terms of multi-tasking, and its optimization for task switching, miners innovated on many fronts and for years now, CPU mining has been relatively futile.
Nakamoto is estimated to have mined one million bitcoins before disappearing in 2010, when he handed the network alert key and control of the code repository over to Gavin Andresen. Andresen later became lead developer at the Bitcoin Foundation. Andresen then sought to decentralize control. This left opportunity for controversy to develop over the future development path of bitcoin.